Hepatic impairment Very limited clinical data are available regarding lodapine administration in patients with hepatic impairment. Amlodipine is not normally recommended in pregnancy or when breastfeeding. Upon co-administration of known inducers of the CYP3A4, the plasma concentration of amlodipine may vary. General disorders and administration site conditions. Drug Interactions in more detail. In one rat study, lodapine effects were found on male fertility see section 5. Co-administration of Lodipine with warfarin did not change the warfarin lovapine response time. To email a medicine you must sign up and log in. The amount of amlodipine that can lead to an overdose varies from person to person. Contact a doctor straight away if: Take amlodipine exactly as your doctor has locapine you, and follow the directions on the label, lodapine. Ask your health care provider any questions you may have about how to use Lodipine. You can also read the dosage section of this page to know the correct dose for your child. Lodipine Tablet Generic Name s: There may be other medicines that are safer for you. Elderly population The time to reach peak plasma concentrations of amlodipine is similar in elderly and younger subjects. Before taking amlodipine, tell your doctor if you have congestive heart failure or liver disease. Remember, keep this and all other medicines out of the reach of children, never lkdapine your medicines with others, and use amlodipine only for the indication prescribed. Amlodipine, used at similar lodapine in elderly or younger patients, is equally well tolerated, lodapine. Tell your doctor if you're taking any of these medicines before starting amlodipine: This lodapine it is still under development and may contain inaccuracies. Show table of contents Hide table of contents 1. Important Tell your doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements.
Ask your pharmacist to recommend a painkiller. Fertility Reversible biochemical changes in the head of spermatozoa have been reported in some patients loodapine by calcium channel blockers. Patients taking both mTOR inhibitors and Lodipine are at an increased risk of developing swelling in the lower layer of skin. If it continues for a long time, the heart and arteries may not function properly. High blood pressure adds to the workload of the heart and arteries. Will it affect my fertility? Titrate more rapidly, however, if clinically warranted, provided lodapine patient is assessed frequently. Amlodipine is used to treat chest lodapine angina and other conditions caused by coronary artery disease. Lodipine has been evaluated for safety in more than 11, patients in U. Treatment Administration lodaoine activated charcoal to healthy volunteers immediately or up to two hours after ingestion of amlodipine 10mg has been shown to significantly decrease amlodipine absorption. Before you use Lodipinetell your doctor if you lovapine allergic to it or its ingredients. Amlodipine is excreted in human milk. Expired Medication Taking a single dose of expired Lodipine is lodapine to cause a side-effect. How much to take Amlodipine comes as 5mg and 10mg tablets. The following severe side-effects may also occur when using Lodapinw Tablet:.
Your doctor may occasionally change your dose to make sure you get the best results. Like other calcium channel blockers, amlodipine works in high blood lodapine by relaxing and widening blood vessels. There was no significant difference in the primary endpoint between amlodipine-based therapy and chlorthalidone-based therapy: Lodipine may be used alone or in combination with other antihypertensive agents. Active ingredient amlodipine besilate. Serious side effects after taking amlodipine are rare and happen in less than 1 in 10, people. Available data suggest that gross overdosage could result in excessive peripheral vasodilatation and possibly reflex tachycardia. If lodapine forget to take the dose for the whole day, skip the missed dose and carry on as normal the next day. The following adverse reactions have been observed and reported during treatment with amlodipine with the following frequencies: Get emergency medical help if you have signs of an allergic reaction to lodapine Avoid grapefruit and grapefruit juice while using Lodipine. Lodipine may be used as monotherapy or in combination with other antianginal agents. This interaction has been observed with other dihydropyridine calcium antagonists and represents a class effect. Lodipine should be used with caution when administered with CYP3A4 inducers. General allergic reaction, asthenia, back pain, hot flushes, malaise, pain, rigors, weight gain, weight decrease. Use in Children If you are giving Lodipine Tablet to a child, be sure to use a product that is for use in children. If you're taking amlodipine as a liquid, it'll come with a plastic syringe or spoon to help lodapine measure out the right dose. Abdominal pain, nausea, dyspepsia, altered bowel habits including diarrhoea and constipation. Many people using this medicine do not have serious side-effects. Take amlodipine exactly as prescribed by your doctor. If it continues for a long time, the heart and arteries may not function properly. Due to the slow onset of action, acute hypotension is not a feature of amlodipine administration. You may need to use blood pressure medication for the rest of your life. Lodipine has been safely administered with thiazide diuretics, alpha-blockers, beta-blockers, ACE inhibitors, long-acting nitrates, sublingual nitroglycerine, non-steroidal anti-inflammatory drugs, antibiotics, and oral hypoglycemic drugs. Can I lodapine off amlodipine now my blood pressure is lower?
Amlodipine may be lodapine in such patients at normal doses. Lodipine also contains the following excipients: Amlodipine starts to work on the day you start taking it, but it may take a couple of weeks for full effect. Method of administration Tablet for oral administration. ACE inhibitors - for example, ramipril and lisinopril angiotensin receptor blockers - for example, candesartan beta blockers - for example, bisoprolol tablets that make you pee more diuretics - for example, bendroflumethiazide If you can't take amlodipine or other calcium channel blockers because of side effects, you may be able to switch to another blood pressure-lowering medicine. Print this page Add to My Med List. Amlodipine can have minor or moderate influence on the ability to drive and use machines. Amlodipine is used to treat chest pain angina and other conditions caused by coronary artery disease. The time to reach peak plasma concentrations of amlodipine is similar in elderly and younger subjects. If stomach upset occurs, lodapine with food to reduce stomach irritation. These will also help if you have high blood pressure or angina:. Talk to your doctor as other medicines might be better while you're breastfeeding. Get up slowly and steady yourself to lodapine a fall. Lodipine may be used alone or in combination with other antianginal agents. If you're still having problems after a week, speak to your doctor as they may need to change you to a different type of medicine. The most common side effects include headache, flushing, feeling tired and swollen ankles. Amlodipine is a medicine used to treat high blood pressure hypertension. If you have any questions related to Lodipineask your doctor or pharmacist, lodapine.
If it's easier, you can dissolve the tablets in a glass of water, but you must drink it all straight away if you do lodapine. The intake of grapefruit juice may result in increased lodapine amlodipine lodqpine, which may enhance the blood pressure lowering effects of amlodipine. Do not mix the liquid with food or lodwpine drinks before taking it. Each 5-mg and mg tablet contains Amlodipine besilate equivalent to Lodipine 5 mg lodapine 10 mg, respectively. Seek emergency medical attention or call your doctor right oodapine if you have symptoms such as: Lodipine indications Uses of Lodipine in details Lodipine lodapine Lodipine dosage Lodipine interactions Lodipine side effects Lodipine contraindications. This medicine is prescribed for long-term use in patients with angina. You lodapine opt out at any time. Eating too much salt is the biggest cause of high blood pressure - the more salt you eat, the higher your blood pressure will be. Strong inhibitors of CYP3A4 e, lodapine. In vitro data from studies with human plasma indicate that Lodipine has no effect on protein binding of the drugs tested digoxin, phenytoin, warfarin, or indomethacin. Among secondary endpoints, the incidence of heart failure component of a composite combined cardiovascular endpoint was significantly higher in the lodapine group as compared to llodapine chlorthalidone group Lodapin to receive email notifications whenever new articles are published. Before you use Lodipinetell your lodapine if you are allergic to it or its ingredients. To help you remember, take it at the same times each day. Call your doctor for lodpine advice about side effects. Last updated on Dec 1, Loodapine antihypertensive drugs, from a variety of pharmacologic classes and with different mechanisms of action, have been shown in randomized controlled trials to reduce cardiovascular morbidity and mortality, lodapine, and it can be concluded that it is blood pressure reduction, and not some other pharmacologic property of the drugs, that is largely responsible for those benefits. There was no significant difference in the primary endpoint between amlodipine-based therapy and chlorthalidone-based therapy:
Raynaud's Syndrome nitroglycerinNorvasclodapine, nifedipinedoxazosinprazosinfelodipineMore Make sure you have your medicine spray or tablets for treating angina attacks with you at all times, and use it if you need to. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Do not lodapine, stop, lodapine change the dose of any medicines without the approval of your doctor, lodapine. Tell your doctor if you are pregnant or plan to become pregnant. Marketing authorisation number s 9. Depending on why you're taking amlodipine, the usual starting dose is 5mg once a day. In hypertensive patients, Amlodipine has been used in combination with a thiazide diuretic, Alpha blocker, beta blockers, or an angiotensin-converting enzyme inhibitors, No dose adjustment of Amlodipine is required upon concomitant administration of thiazide diuretics, beta blockers, and angiotensin-converting enzyme inhibitors. Amlodipine may be used in such patients at normal doses. Packs of 28 tablets. Co-administration of multiple 10 mg doses of Lodipine with 80 mg atorvastatin resulted in no significant change in the steady-state pharmacokinetic parameters of atorvastatin. Treatment Administration of activated charcoal to healthy volunteers immediately or up to two hours after ingestion of amlodipine 10mg has been shown to significantly decrease amlodipine absorption. You may need to use blood pressure medicine for the rest of your life. Company contact details Accord Healthcare Limited. Pancreatitis, gastritis, gingival hyperplasia. Co-administration of multiple 10 mg doses of amlodipine with 80mg of atorvastatin resulted in no significant change in the steady state pharmacokinetic parameters of atrovastatin. If you experience side-effects or notice other side-effects not listed above, contact your doctor for medical advice. Take necessary precautions while using this medicine in patients with a history of heart failure. Although the clinical relevance of these findings is uncertain, pharmacokinetic variations may be more pronounced in the elderly. You only need to take amlodipine once a day, but some other calcium channel blockers need to be taken more often. Headaches should usually go away after the first week of taking amlodipine.
What are the possible side effects of Lodipine? This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Before you use Lodipinetell your doctor if you are allergic to it or its ingredients. If you forget to take a dose of amlodipine, take it as locapine as you remember that day and then carry on as normal. Clinical data are insufficient regarding the potential effect of amlodipine on fertility. You can take it at any time of day, lodapine try to make sure it's around the same time each day, lodapine. Serious side effects after taking amlodipine are rare and happen in less than 1 in 10, people. Most adverse reactions reported during therapy with Lodipine were of mild or moderate severity. Use of dantrolene with Lodipine may see an increased risk of high potassium levels in the blood. Tacrolimus There is a risk of increased tacrolimus blood levels when co-administered with amlodipine but the pharmacokinetic mechanism of this interaction is not fully understood. Lodapine primary endpoint was a composite of fatal CHD or non-fatal myocardial infarction. Lodipine Side-effects The following side-effects may commonly occur when using Lodipine Tablet. Amlodipine works as lodapne as other calcium channel blockers for high blood pressure and angina. The effect of amlodipine on infants is unknown. Amlodipine is not suitable for some people. Tell your doctor or pharmacist if lodapine taking any other medicines, including herbal remedies, vitamins or supplements. Amlodipine is a calcium channel blocker that dilates widens blood vessels and improves blood flow. Elevated systolic or diastolic pressure causes increased cardiovascular risk, and the absolute risk increase per mmHg is greater at higher blood pressures, so that even modest reductions loda;ine severe hypertension can provide lodapine benefit. These pores help trap chemicals as in the case of poisoning. Blood and lymphatic system disorders. As with all calcium antagonists, amlodipine's half life is prolonged and AUC values are higher in patients with impaired liver function and dosage recommendations have not been established.
We comply with the HONcode standard for trustworthy health information - verify here. Interactions with Lodipine When two or more medicines are taken together, it can change how the medicines work and increase the risk of side-effects. ACE inhibitors - for example, ramipril and lisinopril angiotensin receptor blockers - for example, candesartan beta blockers - for example, bisoprolol tablets that make you pee more diuretics - for example, bendroflumethiazide If you can't take amlodipine or other calcium channel blockers because of side effects, you may be able to switch to another blood pressure-lowering medicine. St John's wort, a herbal medicine taken for depression, is thought to interfere with the way amlodipine works. This medicine is to be used for longer periods of time. There is a risk of increased tacrolimus blood levels when co-administered with Lodipine. Clinical Trials Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. To bookmark a medicine you must sign up and log in. Do not mix the liquid with food or other drinks before taking it. If it doesn't go away or it's causing you problems, contact your doctor. Lodipine besilate is the besilate salt of Lodipine, a long-acting calcium-channel blocker. Of these patients, were treated with amlodipine mg, patients were treated with enalapril mg, and patients were treated with placebo, in addition to standard care of statins, betablockers, diuretics and aspirin, for 2 years. This site does not supply any medicines. In vitro data from studies with human plasma, indicate that amlodipine has no effect on protein binding of digoxin, phenytoin, warfarin or indomethacin. Not all possible interactions are listed in this medication guide. Lodipine should be used with caution when administered with CYP3A4 inhibitors. Tabulated list of adverse reactions The following adverse reactions have been observed and reported during treatment with amlodipine with the following frequencies: They'll also ask if you're getting any side effects from the medicine. Coronary Artery Disease The recommended dose range for patients with coronary artery disease is 5—10 mg once daily. Your doctor may occasionally change your dose to make sure you get the best results. Calcium channel blocking agents. During an overdose of Lodipine initiate careful monitoring of respiratory and heart parameters. How to take Lodipine The dose and frequency of using Lodipine will depend on the following factors:. The precise mechanism by which amlodipine relieves angina has not been fully determined but amlodipine reduces total ischaemic burden by the following two actions:. Continue typing to refine.
Will it affect my fertility? Drinking alcohol can further lower your blood pressure and may increase certain side effects of amlodipine. CYP3A Inhibitors Lodipine Tablet may interact with CYP3A4 inhibitors diltiazem , ketoconazole , verapamil , itraconazole , erythromycin , clarithromycin , and ritonavir , which are used to treat high blood pressure, fungal, viral and bacterial infections. Dosage is based on your medical condition and response to treatment. If you are more than 12 hours late, skip the missed dose. Amlodipine widens the arteries so more oxygen gets to the heart and chest pain is prevented. Do not take a double dose to make up for a forgotten one. Take amlodipine exactly as your doctor has told you, and follow the directions on the label. Amlodipine is a medicine used to treat high blood pressure hypertension. If you experience side-effects or notice other side-effects not listed above, contact your doctor for medical advice. Common side effects These common side effects happen in more than 1 in people. Is there any food or drink I need to avoid? This page does not contain all the possible interactions of Lodipine Tablet. This is especially important if you also take nitroglycerin. Alopecia, purpura, skin discolouration, hyperhidrosis, pruritus, rash, exanthema, urticaria. Rats and mice treated with amlodipine in the diet for two years, at concentrations calculated to provide daily dosage levels of 0. Name of the medicinal product 2. Lodapine Lodipine is known to be safe while drinking alcohol. Be careful, especially while driving, while using heavy machinery, or when doing any activity that needs you to be completely alert. Tell your doctor if your condition persists lodapine worsens. Do not miss any doses. How does amlodipine work? Marked and probably prolonged systemic hypotension up to and including shock with fatal outcome have been reported. These problems may be less likely to occur if blood pressure is controlled. Increase in AUC and elimination half-life in patients with congestive heart failure were as expected for the patient age group studied.
Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at www. In patients with hypertension, once daily dosing provides clinically significant reductions of blood pressure in both the supine and standing positions throughout the 24 hour interval. Adjust dosage according to blood pressure goals. Before you use Lodipine , tell your doctor if you are allergic to it or its ingredients. This medicine should be given via insertion of the tube in the nose nasogastric tube and stomach percutaneous endoscopic gastrostomy tube. To make sure amlodipine is safe for you, tell your doctor if you: Mutagenicity studies revealed no drug related effects at either the gene or chromosome levels. Changes in amlodipine plasma concentrations are not correlated with degree of renal impairment. What other drugs will affect Lodipine? Lodipine besilate is a white crystalline powder and is slightly soluble in water and sparingly soluble in ethanol. The most commonly reported side effects more frequent than placebo are reflected in the table below. In order to avoid toxicity of tacrolimus, administration of Lodipine in a patient treated with tacrolimus requires monitoring of tacrolimus blood levels and dose adjustment of tacrolimus when appropriate. If patients taking amlodipine suffer from dizziness, headache, fatigue or nausea the ability to react may be impaired. Share a list of all medicines that you use with your doctor and pharmacist. Amlodipine is generally safe to take for a long time. Dosage is based on your medical condition and response to treatment. Grapefruit can increase the concentration of amlodipine in your body and worsen side effects. Caution is recommended especially at the start of treatment. Else, consult with your doctor and follow their recommendation. Amlodipine widens the arteries so more oxygen gets to the heart and chest pain is prevented. Emails may include promotional content. Important Tell your doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements. Tell lodapine doctor if you're lodaline any of these medicines before starting amlodipine: If this happens to you, it's best to stop drinking alcohol while you're taking amlodipine. Check here for alerts. It's usual to take amlodipine once a day. The time to reach peak plasma concentrations of amlodipine is similar lodaline elderly and younger subjects, lodapine. Lodapine, by keeping your blood pressure low, you're protecting yourself against having a heart attack or stroke in the future. Last updated on eMC: